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Simultaneous detection and fine mapping of quantitative trait loci in mice using heterogeneous stocks.

We describe a method to simultaneously detect and fine map quantitative trait loci (QTL) that is especially suited to the mapping of modifier loci in mouse mutant models. The method exploits the high level of historical recombination present in a heterogeneous stock (HS), an outbred population of mi...

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Bibliografiska uppgifter
Huvudupphovsmän: Mott, Richard, Flint, Jonathan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462050/
https://ncbi.nlm.nih.gov/pubmed/11973314
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