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A method for fine mapping quantitative trait loci in outbred animal stocks

High-resolution mapping of quantitative trait loci (QTL) in animals has proved to be difficult because the large effect sizes detected in crosses between inbred strains are often caused by numerous linked QTLs, each of small effect. In a study of fearfulness in mice, we have shown it is possible to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mott, Richard, Talbot, Christopher J., Turri, Maria G., Collins, Allan C., Flint, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230304397
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