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Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway
Chordomas are radio- and chemo-resistant tumours and metastasise in as many as 40% of patients. The aim of this study was to identify potential molecular targets for the treatment of chordoma. In view of the reported association of chordoma and tuberous sclerosis complex syndrome, and the available...
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| Huvudupphovsmän: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694420/ https://ncbi.nlm.nih.gov/pubmed/19401700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605019 |
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