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Structural and functional consequences of the Milano mutation (R173C) in human apolipoprotein A-I
Carriers of the apolipoprotein A-I(Milano) (apoA-I(M)) variant, R173C, have reduced levels of plasma HDL but no increase in cardiovascular disease. Despite intensive study, it is not clear whether the removal of the arginine or the introduction of the cysteine is responsible for this altered functio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694339/ https://ncbi.nlm.nih.gov/pubmed/19318685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800578-JLR200 |
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