Disruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan

Apolipoprotein A-I (apoA-I) Nichinan, a naturally occurring variant with ΔE235 in the C terminus, is associated with low plasma HDL levels. Here, we investigated the tertiary structure, lipid-binding properties, and ability to induce cellular cholesterol efflux of apoA-I Nichinan and its C-terminal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kono, Momoe, Tanaka, Toshitaka, Tanaka, Masafumi, Vedhachalam, Charulatha, Chetty, Palaniappan S., Nguyen, David, Dhanasekaran, Padmaja, Lund-Katz, Sissel, Phillips, Michael C., Saito, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842158/
https://ncbi.nlm.nih.gov/pubmed/19805625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados