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c-Myc Accelerates S-Phase and Requires WRN to Avoid Replication Stress
c-Myc interacts with components of the pre-replication complex and directly regulates DNA replication [1]. However the consequences of this novel c-Myc function on cell cycle dynamics and replication-associated damage are unknown. Here, we show that c-Myc overexpression in primary human fibroblasts...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694031/ https://ncbi.nlm.nih.gov/pubmed/19554081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005951 |
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