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Increases in Spinal Cerebrospinal Fluid Potassium Concentration Do Not Increase Isoflurane Minimum Alveolar Concentration in Rats

BACKGROUND: Previous studies demonstrated that MAC for isoflurane directly correlates with the concentration of Na(+) in cerebrospinal fluid surrounding the spinal cord, the primary site for mediation of the immobility produced by inhaled anesthetics. If this correlation resulted from increased irri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shnayderman, Dimitry, Laster, Michael J., Eger, Edmond I, Oh, Irene, Zhang, Yi, Jinks, Steven L., Antognini, Joseph F., Raines, Douglas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693418/
https://ncbi.nlm.nih.gov/pubmed/18713900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e3181815f2b
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