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Telomerase activity coevolves with body mass, not lifespan

In multicellular organisms, telomerase is required to maintain telomere length in the germline but is dispensable in the soma. Mice, for example, express telomerase in somatic and germline tissues, while humans express telomerase almost exclusively in the germline. As a result, when telomeres of hum...

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Bibliographische Detailangaben
Hauptverfasser: Seluanov, Andrei, Chen, Zhuoxun, Hine, Christopher, Sasahara, Tais H. C., Ribeiro, Antonio A. C. M., Catania, Kenneth C., Presgraves, Daven C., Gorbunova, Vera
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693359/
https://ncbi.nlm.nih.gov/pubmed/17173545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00262.x
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