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Deletion of Mint Proteins Decreases Amyloid Production in Transgenic Mouse Models of Alzheimer's Disease
Mints/X11s are neuronal adaptor proteins that bind to amyloid-β precursor protein (APP). Previous studies suggested that Mint/X11 proteins influence APP cleavage and affect production of pathogenic amyloid-β (Aβ) peptides in Alzheimer's disease; however, the biological significance of Mint/X11...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Society for Neuroscience
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693334/ https://ncbi.nlm.nih.gov/pubmed/19118172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2481-08.2008 |
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