Загрузка...
Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes
The Sir2 family of proteins are broadly conserved NAD(+)-dependant deacetylases that are implicated in diverse biological processes including DNA regulation, metabolism and longevity. Sir2 proteins are regulated in part by the cellular concentrations of a noncompetitive inhibitor, nicotinamide, that...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693224/ https://ncbi.nlm.nih.gov/pubmed/17289592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.12.022 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|