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Structural Basis for Sirtuin Function: What We Know and What We Don’t
The sirtuin (silent information regulator 2) proteins are NAD(+)-dependent deacetylases that are implicated in diverse biological processes including DNA regulation, metabolism and longevity. Homologues of the prototypic yeast Sir2p have been identified in all three kingdoms of life, and while bacte...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886166/ https://ncbi.nlm.nih.gov/pubmed/19766737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.09.009 |
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