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The Extracellular Domain of p75(NTR) Is Necessary to Inhibit Neurotrophin-3 Signaling through TrkA
The TrkA receptor is activated primarily by nerve growth factor (NGF), but it can also be activated by high concentrations of neurotrophin 3 (NT-3). The pan-neurotrophin receptor p75(NTR) strongly inhibits activation of TrkA by NT-3 but not by NGF. To examine the role of p75(NTR) in regulating the s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693057/ https://ncbi.nlm.nih.gov/pubmed/11150291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M005132200 |
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