A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study

BACKGROUND: An attenuation of the insulin-like growth factor 1 (IGF-1) signaling has been associated with elongation of the lifespan in simple metazoan organisms and in rodents. In humans, IGF-1 level has an age-related modulation with a lower concentration in the elderly, depending on hormonal and...

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Hlavní autoři: Albani, Diego, Batelli, Sara, Polito, Letizia, Vittori, Angelica, Pesaresi, Marzia, Gajo, Giovanni Battista, De Angeli, Sergio, Zanardo, Andrea, Gallucci, Maurizio, Forloni, Gianluigi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692840/
https://ncbi.nlm.nih.gov/pubmed/19460140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2318-9-19
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