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The molecular genetics of sirtuins: association with human longevity and age-related diseases

The sirtuins are a family of proteins remarkably conserved from yeast to humans. In organisms such as yeast, worms and flies it is quite well established that the activity of sirtuins prolongs lifespan. As a result of promising findings in simple organisms, sirtuins are now investigated in higher or...

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Detalhes bibliográficos
Main Authors: Polito, Letizia, Kehoe, Patrick G, Forloni, Gianluigi, Albani, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076766/
https://ncbi.nlm.nih.gov/pubmed/21537393
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