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Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction

Infections produce severe respiratory muscle dysfunction. It is known that the proteasome proteolytic system is activated in skeletal muscle in sepsis, and it has been postulated that this degradative pathway is responsible for inducing skeletal muscle weakness and wasting. The objective of this stu...

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Detalhes bibliográficos
Main Authors: Supinski, G. S., Vanags, J., Callahan, L. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692801/
https://ncbi.nlm.nih.gov/pubmed/19376888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90404.2008
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