Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

Interactions between developmental signaling pathways govern the formation and function of stem cells. Prostaglandin (PG) E2 regulates vertebrate hematopoietic stem cells (HSC). Similarly, the Wnt signaling pathway controls HSC self-renewal and bone marrow repopulation. Here, we show that wnt report...

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Detalhes bibliográficos
Main Authors: Goessling, Wolfram, North, Trista E., Loewer, Sabine, Lord, Allegra M., Lee, Sang, Stoick-Cooper, Cristi L., Weidinger, Gilbert, Puder, Mark, Daley, George Q., Moon, Randall T., Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692708/
https://ncbi.nlm.nih.gov/pubmed/19303855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.015
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