Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

Interactions between developmental signaling pathways govern the formation and function of stem cells. Prostaglandin (PG) E2 regulates vertebrate hematopoietic stem cells (HSC). Similarly, the Wnt signaling pathway controls HSC self-renewal and bone marrow repopulation. Here, we show that wnt report...

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Bibliographische Detailangaben
Hauptverfasser: Goessling, Wolfram, North, Trista E., Loewer, Sabine, Lord, Allegra M., Lee, Sang, Stoick-Cooper, Cristi L., Weidinger, Gilbert, Puder, Mark, Daley, George Q., Moon, Randall T., Zon, Leonard I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692708/
https://ncbi.nlm.nih.gov/pubmed/19303855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.015
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