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Mineralocorticoid Receptor Antagonism Attenuates Vascular Apoptosis and Injury via Rescuing Akt Activation

Emerging evidence indicates that mineralocorticoid receptor (MR) blockade reduces the risk of cardiovascular events beyond those predicted by its blood pressure (BP)-lowering actions; however, the underlying mechanisms remain unclear. To investigate whether protection elicited by MR blockade is thro...

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Detalhes bibliográficos
Main Authors: Wei, Yongzhong, Whaley-Connell, Adam T., Habibi, Javad, Rehmer, Jenna, Rehmer, Nathan, Patel, Kamlesh, Hayden, Melvin, DeMarco, Vincent, Ferrario, Carlos M., Ibdah, Jamal A., Sowers, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692525/
https://ncbi.nlm.nih.gov/pubmed/19114643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.121954
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