Nebivolol Reduces Proteinuria and Renal NADPH Oxidase-Generated Reactive Oxygen Species in the Transgenic Ren2 Rat

BACKGROUND/AIMS: Renin-angiotensin-aldosterone system (RAAS) and sympathetic nervous system activation are crucial in the pathogenesis of hypertension, cardiovascular and renal disease. NADPH oxidase-mediated increases in reactive oxygen species (ROS) are an important mediator for RAAS-induced cardi...

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Detalhes bibliográficos
Main Authors: Whaley-Connell, Adam, Habibi, Javad, Johnson, Megan, Tilmon, Roger, Rehmer, Nathan, Rehmer, Jenna, Wiedmeyer, Charles, Ferrario, Carlos M., Sowers, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Original Report: Laboratory Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814025/
https://ncbi.nlm.nih.gov/pubmed/19609077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000229305
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