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Contrasting Features of Urea Cycle Disorders in Human Patients and Knockout Mouse Models

The urea cycle exists for the removal of excess nitrogen from the body. Six separate enzymes comprise the urea cycle, and a deficiency in any one of them causes a urea cycle disorder (UCD) in humans. Arginase is the only urea cycle enzyme with an alternate isoform, though no known human disorder cur...

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Bibliografski detalji
Glavni autori: Deignan, Joshua L., Cederbaum, Stephen D., Grody, Wayne W.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692509/
https://ncbi.nlm.nih.gov/pubmed/17933574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.08.123
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