Expression and Biochemical Characterization of Plasmodium falciparum DNA Ligase I

We report that Plasmodium falciparum (Pf) encodes a 912 amino acid ATP-dependent DNA ligase. Protein sequence analysis of Pf DNA Ligase I indicates a strong sequence similarity, particularly in the C-terminal region, to DNA ligase I homologues. The activity of recombinant Pf DNA Ligase I (PfLigI) wa...

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Main Authors: Buguliskis, Jeffrey S., Casta, Louis J., Butz, Charles E., Matsumoto, Yoshihiro, Taraschi, Theodore F.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692355/
https://ncbi.nlm.nih.gov/pubmed/17688957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.06.011
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