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EXPRESSION AND BIOCHEMICAL CHARACTERIZATION OF THE PLASMODIUM FALCIPARUM DNA REPAIR ENZYME, FLAP ENDONUCLEASE-1 (PfFEN-1)

Flap Endonuclease-1 (FEN-1) is a structure-specific endonuclease that is critical for the resolution of single-stranded DNA flap intermediates that form during long patch DNA Base Excision Repair (BER). This investigation reports that Plasmodium species encode FEN-1 homologs. Protein sequence analys...

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Main Authors: Casta, Louis J., Buguliskis, Jeffery S., Matsumoto, Yoshihiro, Taraschi, Theodore F.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699572/
https://ncbi.nlm.nih.gov/pubmed/17928073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.08.008
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