Synthesis of 1-β-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus

There are no FDA approved drugs for the treatment of hemorrhagic fever with renal syndrome (HFRS), a serious human illnesses caused by hantaviruses. Clinical studies using ribavirin (RBV) to treat HFRS patients suggest that it provides an improved prognosis when given early in the course of disease....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chung, Dong-Hoon, Kumarapperuma, Sidath C., Sun, Yanjie, Li, Qianjun, Chu, Yong-Kyu, Arterburn, Jeffrey B., Parker, William B., Smith, Jeffrey, Spik, Kristin, Ramanathan, Harish, Schmaljohn, Connie S., Jonsson, Colleen B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692291/
https://ncbi.nlm.nih.gov/pubmed/18394724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.02.003
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