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Synthesis of the AB Subunit of Angelmicin B through a Tandem Alkoxy Radical Fragmentation-Etherification Sequence
[Image: see text] The synthesis of the tricyclic enone 2, corresponding to the AB subunit of the novel tyrosine kinase inhibitor angelmicin B, is described. The strategy centers on an intramolecular Diels—Alder (IMDA) reaction on triene 4 to provide the complex decalin 3, which is elaborated to 2. O...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692225/ https://ncbi.nlm.nih.gov/pubmed/18324819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol703036y |
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