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2D IR Provides Evidence of an Intermediate in the Membrane-catalyzed Assembly of Diabetic Amyloid
Islet amyloid polypeptide (IAPP, also known as amylin) is responsible for pancreatic amyloid deposits in type 2 diabetes. The deposits, as well as intermediates in their assembly, are cytotoxic to pancreatic β-cells and contribute to the loss of β-cell mass associated with type 2 diabetes. The facto...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692222/ https://ncbi.nlm.nih.gov/pubmed/19182939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp810261x |
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