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New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential
The molecular chaperone Hsp90 (heat shock protein 90) is a promising target in cancer therapy. Preclinical and clinical evaluations of a variety of Hsp90 inhibitors have shown antitumor effect as a single agent and in combination with chemotherapy. Current Hsp90 inhibitors are categorized into sever...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692088/ https://ncbi.nlm.nih.gov/pubmed/19179103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2008.12.002 |
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