Tuberous Sclerosis Complex Activity Is Required to Control Neuronal Stress Responses in an mTOR-Dependent Manner

Tuberous sclerosis complex (TSC) is a neurogenetic disorder caused by loss-of-function mutations in either the TSC1 or TSC2 genes and frequently results in prominent CNS manifestations, including epilepsy, mental retardation, and autism spectrum disorder. The TSC1/TSC2 protein complex plays a major...

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Autors principals: Di Nardo, Alessia, Kramvis, Ioannis, Cho, Namjik, Sadowski, Abbey, Meikle, Lynsey, Kwiatkowski, David J., Sahin, Mustafa
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691854/
https://ncbi.nlm.nih.gov/pubmed/19420259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0778-09.2009
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