Aven-dependent activation of ATM following DNA damage

BACKGROUND: In response to DNA damage, cells either undergo cell cycle arrest or apoptosis, depending on the extent of damage and the cell’s capacity for DNA repair. Cell cycle arrest induced by double-stranded DNA breaks depends on activation of the ataxia-telangiectasia (ATM) protein kinase, which...

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Detalhes bibliográficos
Main Authors: Guo, Jessie Yanxiang, Yamada, Ayumi, Kajino, Taisuke, Wu, Judy Qiju, Tang, Wanli, Freel, Christopher D., Feng, Junjie, Chau, B. Nelson, Wang, Michael Zhuo, Margolis, Seth, Yoo, Hae Yong, Wang, Xiao-Fan, Dunphy, William G., Irusta, Pablo M., Hardwick, J. Marie, Kornbluth, Sally
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691717/
https://ncbi.nlm.nih.gov/pubmed/18571408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.05.045
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