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Maintenance of CSF arrest: A role for Cdc2 and PP2A-mediated regulation of Emi2
BACKGROUND: Vertebrate oocytes are arrested in metaphase II of meiosis prior to fertilization by cytostatic factor (CSF). CSF enforces a cell cycle arrest by inhibiting the anaphase promoting complex (APC), an E3 ubiquitin ligase that targets Cyclin B for degradation. Although Cyclin B synthesis is...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790409/ https://ncbi.nlm.nih.gov/pubmed/17276914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.12.045 |
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