Maintenance of CSF arrest: A role for Cdc2 and PP2A-mediated regulation of Emi2

BACKGROUND: Vertebrate oocytes are arrested in metaphase II of meiosis prior to fertilization by cytostatic factor (CSF). CSF enforces a cell cycle arrest by inhibiting the anaphase promoting complex (APC), an E3 ubiquitin ligase that targets Cyclin B for degradation. Although Cyclin B synthesis is...

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Main Authors: Wu, Qiju, Guo, Yanxiang, Yamada, Ayumi, Perry, Jennifer A., Wang, Michael Z., Araki, Marito, Freel, Christopher D., Tung, Jeffrey J., Tang, Wanli, Margolis, Seth S., Jackson, Peter K., Yamano, Hiroyuki, Asano, Maki, Kornbluth, Sally
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790409/
https://ncbi.nlm.nih.gov/pubmed/17276914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.12.045
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