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Factors affecting counteraction by methylamines of urea effects on aldose reductase
The concentration of urea in renal medullary cells is high enough to affect enzymes seriously by reducing V(max) or raising K(m), yet the cells survive and function. The usual explanation is that the methylamines found in the renal medulla, namely glycerophosphocholine and betaine, have actions oppo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC26914/ https://ncbi.nlm.nih.gov/pubmed/10339620 |
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