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Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Tizanidine Hydrochloride Tablets

The study aim was concerned with formulation and evaluation of bioadhesive buccal drug delivery of tizanidine hydrochloride tablets, which is extensively metabolized by liver. The tablets were prepared by direct compression using bioadhesive polymers such as hydroxylpropyl methylcellulose K4M, sodiu...

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Main Authors: Shanker, Gazzi, Kumar, Chegonda K., Gonugunta, Chandra Sekhara Rao, Kumar, B. Vijaya, Veerareddy, Prabhakar Reddy
格式: Artigo
語言:Inglês
出版: Springer US 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690804/
https://ncbi.nlm.nih.gov/pubmed/19424804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9241-2
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