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Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Tizanidine Hydrochloride Tablets

The study aim was concerned with formulation and evaluation of bioadhesive buccal drug delivery of tizanidine hydrochloride tablets, which is extensively metabolized by liver. The tablets were prepared by direct compression using bioadhesive polymers such as hydroxylpropyl methylcellulose K4M, sodiu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shanker, Gazzi, Kumar, Chegonda K., Gonugunta, Chandra Sekhara Rao, Kumar, B. Vijaya, Veerareddy, Prabhakar Reddy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690804/
https://ncbi.nlm.nih.gov/pubmed/19424804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9241-2
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