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Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Tizanidine Hydrochloride Tablets

The study aim was concerned with formulation and evaluation of bioadhesive buccal drug delivery of tizanidine hydrochloride tablets, which is extensively metabolized by liver. The tablets were prepared by direct compression using bioadhesive polymers such as hydroxylpropyl methylcellulose K4M, sodiu...

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Autors principals: Shanker, Gazzi, Kumar, Chegonda K., Gonugunta, Chandra Sekhara Rao, Kumar, B. Vijaya, Veerareddy, Prabhakar Reddy
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690804/
https://ncbi.nlm.nih.gov/pubmed/19424804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9241-2
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