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The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

IL-33 is a chromatin-associated cytokine of the IL-1 family that has recently been linked to many diseases, including asthma, rheumatoid arthritis, atherosclerosis, and cardiovascular diseases. IL-33 signals through the IL-1 receptor-related protein ST2 and drives production of pro-inflammatory and...

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Bibliographic Details
Main Authors: Cayrol, Corinne, Girard, Jean-Philippe
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690027/
https://ncbi.nlm.nih.gov/pubmed/19439663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812690106
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