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IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

Interleukin-33 (IL-33) (NF-HEV) is a chromatin-associated nuclear cytokine from the IL-1 family, which has been linked to important diseases, including asthma, rheumatoid arthritis, ulcerative colitis, and cardiovascular diseases. IL-33 signals through the ST2 receptor and drives cytokine production...

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Detalhes bibliográficos
Main Authors: Lefrançais, Emma, Roga, Stephane, Gautier, Violette, Gonzalez-de-Peredo, Anne, Monsarrat, Bernard, Girard, Jean-Philippe, Cayrol, Corinne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277172/
https://ncbi.nlm.nih.gov/pubmed/22307629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115884109
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