Genome-Wide Identification of Alternative Splice Forms Down-Regulated by Nonsense-Mediated mRNA Decay in Drosophila

Alternative mRNA splicing adds a layer of regulation to the expression of thousands of genes in Drosophila melanogaster. Not all alternative splicing results in functional protein; it can also yield mRNA isoforms with premature stop codons that are degraded by the nonsense-mediated mRNA decay (NMD)...

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Autors principals: Hansen, Kasper Daniel, Lareau, Liana F., Blanchette, Marco, Green, Richard E., Meng, Qi, Rehwinkel, Jan, Gallusser, Fabian L., Izaurralde, Elisa, Rio, Donald C., Dudoit, Sandrine, Brenner, Steven E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689934/
https://ncbi.nlm.nih.gov/pubmed/19543372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000525
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