Leukotriene B4 Release from Mast Cells in IgE-Mediated Airway Hyperresponsiveness and Inflammation

Previous studies have shown that leukotriene B4 (LTB4), a proinflammatory lipid mediator, is linked to the development of airway hyperresponsiveness through the accumulation of IL-13–producing CD8+ T cells, which express a high affinity receptor for LTB4, BLT1 (Miyahara et al., Am J Respir Crit Care...

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Autores principales: Miyahara, Nobuaki, Ohnishi, Hiroshi, Miyahara, Satoko, Takeda, Katsuyuki, Matsubara, Shigeki, Matsuda, Hiroyuki, Okamoto, Masakazu, Loader, Joan E., Joetham, Anthony, Tanimoto, Mitsune, Dakhama, Azzeddine, Gelfand, Erwin W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689918/
https://ncbi.nlm.nih.gov/pubmed/19029019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0095OC
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