Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells

Interleukin-10 (IL-10) is intensely studied, yet little is known about the mechanisms that control IL-10 expression. We identified striking similarities between IL-10 and interferon-γ (IFN-γ) regulation in mouse natural killer (NK) cells. Like IFN-γ, IL-10 expression is induced by IL-2 and IL-12 and...

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Main Authors: Grant, LR, Yao, Z-J, Hedrich, CM, Wang, F, Moorthy, A, Wilson, K, Ranatunga, D, Bream, JH
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689787/
https://ncbi.nlm.nih.gov/pubmed/18401353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2008.20
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