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A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome
Interleukin (IL)-10 is an immunoregulatory cytokine that is produced by diverse cell populations. Studies in mice suggest that the cellular source of IL-10 is a key determinant in various disease pathologies, yet little is known regarding the control of tissue-specific human IL-10 expression. To ass...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761349/ https://ncbi.nlm.nih.gov/pubmed/19805095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904955106 |
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