A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

Interleukin (IL)-10 is an immunoregulatory cytokine that is produced by diverse cell populations. Studies in mice suggest that the cellular source of IL-10 is a key determinant in various disease pathologies, yet little is known regarding the control of tissue-specific human IL-10 expression. To ass...

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Bibliografski detalji
Glavni autori: Ranatunga, Dilini, Hedrich, Christian M., Wang, Fengying, McVicar, Daniel W., Nowak, Nathan, Joshi, Trupti, Feigenbaum, Lionel, Grant, Lindsay R., Stäger, Simona, Bream, Jay H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761349/
https://ncbi.nlm.nih.gov/pubmed/19805095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904955106
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