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Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane

As with Usher syndrome observed in humans, the two main phenotypes of the tubby mouse are progressive hearing loss and retinal degeneration. Yet, the mechanism underlying the tub-related cochlear degeneration is still unclear. The reduction/oxidation (redox) imbalance in the cell is related to many...

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Bibliographic Details
Main Authors: Kong, Li, Chen, Guang-Di, Zhou, Xiaohong, McGinnis, James F., Li, Feng, Cao, Wei
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689618/
https://ncbi.nlm.nih.gov/pubmed/19114066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2008.08.013
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