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Neuroprotective Effect of Over Expression of Thioredoxin on Photoreceptor Degeneration in Tubby Mice

The tubby mouse is a phenotypic model for sensorineural deafness and retinal dystrophy including Usher Syndrome Type 1. Thioredoxin is a small 13 kDa protein which, when ubiquitously expressed as a transgene in the mouse, provides protection against multiple disease states including light-induced an...

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Detalhes bibliográficos
Main Authors: Kong, Li, Zhou, Xiaohong, Li, Feng, Yodoi, Juni, McGinnis, James, Cao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919840/
https://ncbi.nlm.nih.gov/pubmed/20298786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.03.005
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