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Neuroprotective Effect of Over Expression of Thioredoxin on Photoreceptor Degeneration in Tubby Mice
The tubby mouse is a phenotypic model for sensorineural deafness and retinal dystrophy including Usher Syndrome Type 1. Thioredoxin is a small 13 kDa protein which, when ubiquitously expressed as a transgene in the mouse, provides protection against multiple disease states including light-induced an...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919840/ https://ncbi.nlm.nih.gov/pubmed/20298786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.03.005 |
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