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Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane
As with Usher syndrome observed in humans, the two main phenotypes of the tubby mouse are progressive hearing loss and retinal degeneration. Yet, the mechanism underlying the tub-related cochlear degeneration is still unclear. The reduction/oxidation (redox) imbalance in the cell is related to many...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689618/ https://ncbi.nlm.nih.gov/pubmed/19114066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2008.08.013 |
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