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Analysis of the fitness effect of compensatory mutations

This paper extends previous work on the Darwinian evolutionary fitness effect of the fixation of deleterious mutations by incorporating compensatory mutations, which are mutations (deleterious by themselves) that ameliorate other deleterious mutations, thus reducing the genetic load of populations....

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Autors principals: Zhang, Liqing, Watson, Layne T.
Format: Artigo
Idioma:Inglês
Publicat: HFSP Publishing 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689613/
https://ncbi.nlm.nih.gov/pubmed/19649156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2990075
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