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The cardiac force-frequency relationship and frequency-dependent acceleration of relaxation are impaired in lipopolysaccharide-treated rats: is the phospholamban-SERCA axis a therapeutic target?

Sepsis-induced myocardial dysfunction has traditionally been thought of as principally affecting systolic heart function. One of the primary reasons for this concept is that systolic dysfunction is relatively easy to conceptualize, visualize, and measure. With the advent of preload-independent measu...

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Detalhes bibliográficos
Main Authors: Heitner, Stephen B, Hollenberg, Steven M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689476/
https://ncbi.nlm.nih.gov/pubmed/19439042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7752
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