An efficient variance component approach implementing an average information REML suitable for combined LD and linkage mapping with a general complex pedigree

Variance component (VC) approaches based on restricted maximum likelihood (REML) have been used as an attractive method for positioning of quantitative trait loci (QTL). Linkage disequilibrium (LD) information can be easily implemented in the covariance structure among QTL effects (e.g. genotype rel...

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Hlavní autoři: Lee, Sang Hong, Werf, Julius HJ van der
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689296/
https://ncbi.nlm.nih.gov/pubmed/16451790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-38-1-25
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