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Simultaneous fine mapping of closely linked epistatic quantitative trait loci using combined linkage disequilibrium and linkage with a general pedigree

Causal mutations and their intra- and inter-locus interactions play a critical role in complex trait variation. It is often not easy to detect epistatic quantitative trait loci (QTL) due to complicated population structure requirements for detecting epistatic effects in linkage analysis studies and...

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Hlavní autoři: Lee, Sang Hong, Werf, Julius HJ van der
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674901/
https://ncbi.nlm.nih.gov/pubmed/18400149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-40-3-265
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