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The efficiency of designs for fine-mapping of quantitative trait loci using combined linkage disequilibrium and linkage

In a simulation study, different designs were compared for efficiency of fine-mapping of QTL. The variance component method for fine-mapping of QTL was used to estimate QTL position and variance components. The design of many families with small size gave a higher mapping resolution than a design wi...

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Sonraí Bibleagrafaíochta
Main Authors: Lee, Sang Hong, Werf, Julius HJ van der
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697183/
https://ncbi.nlm.nih.gov/pubmed/15040896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-36-2-145
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