High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples

Acute promyelocytic leukemia (APL) is characterized by the t(15;17) chromosomal translocation, which results in fusion of the retinoic acid receptor α (RARA) gene to another gene, most commonly promyelocytic leukemia (PML). The resulting fusion protein, PML-RARA, initiates APL, which is a subtype (M...

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Detalhes bibliográficos
Main Authors: Payton, Jacqueline E., Grieselhuber, Nicole R., Chang, Li-Wei, Murakami, Mark, Geiss, Gary K., Link, Daniel C., Nagarajan, Rakesh, Watson, Mark A., Ley, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689138/
https://ncbi.nlm.nih.gov/pubmed/19451695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38248
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