Computational identification of the normal and perturbed genetic networks involved in myeloid differentiation and acute promyelocytic leukemia

BACKGROUND: Acute myeloid leukemia (AML) comprises a group of diseases characterized by the abnormal development of malignant myeloid cells. Recent studies have demonstrated an important role for aberrant transcriptional regulation in AML pathophysiology. Although several transcription factors (TFs)...

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Detalhes bibliográficos
Main Authors: Chang, Li Wei, Payton, Jacqueline E, Yuan, Wenlin, Ley, Timothy J, Nagarajan, Rakesh, Stormo, Gary D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374711/
https://ncbi.nlm.nih.gov/pubmed/18291030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-2-r38
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