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Pathogenesis of holoprosencephaly

Holoprosencephaly (HPE), the most common human forebrain malformation, occurs in 1 in 250 fetuses and 1 in 16,000 live births. HPE is etiologically heterogeneous, and its pathology is variable. Several mouse models of HPE have been generated, and some of the molecular causes of different forms of HP...

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Detalhes bibliográficos
Main Authors: Geng, Xin, Oliver, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689134/
https://ncbi.nlm.nih.gov/pubmed/19487816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38937
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